姓名：吴菲  项目研究员

籍贯：湖北

联系电话：010-62561782

电子邮箱：wufei317@iccas.ac.cn

 

研究方向：

生物电化学及生物电催化基础研究，蛋白质的界面电化学行为调控；

结合化学修饰和生物工程的蛋白酶改造，重点关注金属蛋白酶的功能设计与改造；

基于生物电化学界面的活体传感与调控

 

教育及工作背景：

2018.3 - 至今                    中科院化学研究所                    副研究员

2017.12 – 2018.2             中科院化学研究所                    助理研究员

2015.09~2017.12             中国科学院化学研究所            博士后

2010.08~2015.07             美国犹他大学                           博士

2005.09~2009.06             南开大学                                  学士

 

发表文章：

迄今已在Chem. Soc. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Anal. Chem.等学术期刊发表研究论文40篇，论文他引600余次。

近期代表性论文：

 

1. Shuyue Guo, Ping Yu, Weiqi Li, Yuanping Yi, Fei Wu*, Lanqun Mao*, Electron hopping by interfacing semiconducting graphdiyne nanosheets and redox molecules for selective electrocatalysis, J. Am. Chem. Soc. 2020, 142, 2074-2082.

 

2. Huan Wei, Lijuan Li, Jing Jin, Fei Wu*, Ping Yu, Furong Ma, Lanqun Mao*, Galvanic redox potentiometry based microelectrode array for synchronous ascorbate and single-unit recordings in rat brain, Anal. Chem. 2020, 92, 10177-10182.

3. Huan Wei, Fei Wu*, Lijuan Li, Xiaoti Yang, Cong Xu, Ping Yu, Furong Ma, Lanqun Mao*, Natural leukocyte membrane-masked microelectrodes with an enhanced antifouling ability and biocompatibility for in vivo electrochemical sensing, Anal. Chem. 2020, 92, 11374-11379.

4. Zhongjie Han, Lijun Zhao, Ping Yu, Jiwen Chen*, Fei Wu*, Lanqun Mao, Comparative investigation of small laccase immobilized on carbon nanomaterials for direct bioelectrocatalysis of oxygen reduction, Electrochem. Commun. 2019, 101, 82-87.

5. Fei Wu, Ping Yu, Xiaoti Yang, Zhongjie Han, Ming Wang, Lanqun Mao*, Exploring ferredoxin-dependent glutamate synthase as an enzymatic bioelectrocatalyst, J. Am. Chem. Soc. 2018, 140, 12700-12704.

6. Fei Wu, Hanjun Cheng, Huan Wei, Tianyi Xiong, Ping Yu, Lanqun Mao*, Galvanic redox potentiometry for self-driven in vivo measurement of neurochemical dynamics at open-circuit potential, Anal. Chem. 2018, 90, 13021-13029.

7. Fei Wu, Ping Yu, Lanqun Mao*, Analytical and quantitative in vivo monitoring of brain neurochemistry by electrochemical and imaging approaches, ACS Omega 2018,3, 13267-13274.

8. Fei Wu^#, Lei Su^#, Ping Yu, Lanqun Mao*, Role of organic solvents in immobilizing fungus laccase on single-walled carbon nanotubes for improved current response in direct bioelectrocatalysis, J. Am. Chem. Soc. 2017, 139, 1565-1574.

9. Fei Wu, Ping Yu, Lanqun Mao*, Self-powered electrochemical systems as neurochemical sensors: toward self-triggered in vivo analysis of brain chemistry, Chem. Soc. Rev. 2017, 46, 2692-2704.

10. Fei Wu, Ping Yu, Lanqun Mao*, Bioelectrochemistry for in vivo analysis: interface engineering toward implantable electrochemical biosensors, Curr. Opin. Electrochem. 2017, 5, 152-157.

11. Fei Wu, Shelley D. Minteer*, Krebs cycle metabolon: structural evidence of substrate channeling revealed by cross-linking and mass spectrometry, Angew. Chem. Int. Ed. 2015, 54, 1851-1854.

12. Fei Wu, Lindsey N. Pelster, Shelley D. Minteer*, Krebs cycle metabolon formation: metabolite concentration gradient enhanced compartmentation of sequential enzymes, Chem. Commun. 2015, 51, 1244-1247.

 

基金及获奖情况：

2019年                        国家重点研发计划                                                                      研究骨干

2018年                        入选"2018-2020年度中国科协青年人才托举工程"项目

2018年                        国家自然科学基金面上项目                                                        主持

2015年                        支持"率先行动"联合资助优秀博士后项目                                   主持